Evolución y calidad de vida a los tres meses tras hospitalización por neumonía COVID / Evolution and quality of life at three months after hospitalization for COVID pneumonia

Objetivo: Conocer la evolución y calidad de vida relacionada con la salud a los tres meses del alta, en pacientes que fueron hospitalizados en el hospital de Fuenlabrada con diagnóstico de neumonía por COVID-19, valorados por el Servicio de Rehabilitación y que realizaron fisioterapia. Métodos: Se recogen datos de 59 pacientes, diferenciando los que fueron valorados en UCI (41 pacientes), de los valorados en planta de hospitalización (18). Los datos se toman de su historia clínica electrónica, y se realiza una entrevista telefónica tres meses después del alta hospitalaria. Se analizan datos de su evolución durante hospitalización, tras el alta y durante los meses siguientes, y de su situación en el momento de la entrevista. Se pide a los pacientes una valoración de la fisioterapia recibida y que contesten el cuestionario de calidad de vida relacionado con la salud SF-36. Resultados: Estos pacientes han tenido la peor evolución de su neumonía COVID de entre los ingresados en nuestro hospital, pero tuvieron una buena recuperación funcional con la fisioterapia intrahospitalaria recibida, la cual fue valorada muy positivamente por los pacientes. Después de tres meses, el 84% tienen síntomas persistentes, siendo los más frecuentes disnea, cansancio y depresión/ansiedad, y tienen peores puntuaciones en SF-36 que la población de referencia. Conclusiones: La mayoría de los pacientes que requieren rehabilitación durante su hospitalización por neumonía COVID-19, tienen síntomas persistentes y perciben un deterioro de su calidad de vida relacionada con la salud, tras tres meses del alta hospitalaria.(AU)

Objective: Assess clinical evolution and health-related quality of life at three months after discharge in patients who were admitted and diagnosed with COVID-19 pneumonia, evaluated by the Rehabilitation Service and received physiotherapy in Fuenlabrada Hospital. Methods: Data were collected from 59 patients, separating those who were assessed in ICU (41 patients) from those assessed in the hospital ward (18). Data were obtained from their Electronic Medical Record, and a telephone interview was performed three months after their discharge. Data about their clinical progress during their hospitalization, after discharge, over the next months and their condition at the time of the interview is analyzed. Patients were asked to assess the quality of the physiotherapy received and to answer the SF-36 health-related quality of life questionnaire. Results: These patients had the worst progress of the COVID pneumonia among all patients hospitalized in our hospital, but they had a good functional recovery with the inpatient physiotherapy received, which was positively rated. After three months, 84% have persistent symptoms, with the most common being dyspnoea, fatigue and anxiety/depression, and score worse in the SF-36 questionnaire than the reference population. Conclusions: Most patients who require rehabilitation during their COVID pneumonia admission have persistent symptoms and perceive a deterioration in their health-related quality of life after three months of discharge.(AU)

[Evolution and quality of life at three months after hospitalization for COVID pneumonia]. / Evolución y calidad de vida a los tres meses tras hospitalización por neumonía COVID.

OBJECTIVE: Assess clinical evolution and health-related quality of life at three months after discharge in patients who were admitted and diagnosed with COVID-19 pneumonia, evaluated by the Rehabilitation Service and received physiotherapy in Fuenlabrada Hospital. METHODS: Data were collected from 59 patients, separating those who were assessed in ICU (41 patients) from those assessed in the hospital ward (18). Data were obtained from their Electronic Medical Record, and a telephone interview was performed three months after their discharge. Data about their clinical progress during their hospitalization, after discharge, over the next months and their condition at the time of the interview is analyzed. Patients were asked to assess the quality of the physiotherapy received and to answer the SF-36 health-related quality of life questionnaire. RESULTS: These patients had the worst progress of the COVID pneumonia among all patients hospitalized in our hospital, but they had a good functional recovery with the inpatient physiotherapy received, which was positively rated. After three months, 84% have persistent symptoms, with the most common being dyspnoea, fatigue and anxiety/depression, and score worse in the SF-36 questionnaire than the reference population. CONCLUSIONS: Most patients who require rehabilitation during their COVID pneumonia admission have persistent symptoms and perceive a deterioration in their health-related quality of life after three months of discharge.

Evaluación a los dos meses del alta hospitalaria tras la primera ola de COVID-19: presencia de síntomas persistentes / Assessment of hospitalized covid-19 patients two month after discharge: characterization of persistent symptoms

Introduction: a series of symptoms have been reported after COVID-19, which have been encompassed in the so-named “postCOVID syndrome”. PostCOVID syndrome is a heterogeneous disorder with an uncertain pathophysiology. The aim of this study is to describe the characteristics and frequence of symptoms after COVID-19 discharge and to analyze the possible implicated factors. Methods: this is an observational propective study with COVID-19 patients hospitalized from March to April 2020. Patients were assessed in an outpatient clinic two months after discharge, and serological, radiological and laboratory workup was conducted. Previous medical history, length of stay (LOS) and intensive care unit (ICU) admission were recorded. Persistent symptons (PS) were defined as those appearing after the acute infection and present at follow-up. Results: 74 patients were included. Mean age was 66±13 years, and 54.4% patients were men. Six (8.1%) patients needed ICU admission, and median LOS was 8 (6-12) days. Forty (54.8%) patients presented PS, the most frequent being fatigue and dyspnea (20.3% each). 77% patients presented laboratory abnormalities but just in 11 cases (15.1%) were they severe. Ten (13.5%) had radiological abnormalities. 71 (95.9%) had positive IgG serology. There were no differences between patients with and without PS regarding previous medical history or acute infection course. PS patients had a higher heart rate 83 (75-93) vs 76 65-85) bpm; p=0.038) at assessment. Conclusion: symptoms and laboratory abnormalities are frequent two months after COVID-19, although usually mild. No predictors... (AU)

Introducción: se han notificado tras el alta por COVID-19 una serie de síntomas englobados dentro del llamado “síndrome post-COVID”, un cuadro heterogéneo cuya fisiopatología es incierta. Nuestro objetivo es describir las características y frecuencia de síntomas tras el alta y analizar los posibles factores relacionados. Métodos: estudio observacional prospectivo con pacientes ingresados por COVID-19 durante marzo-abril de 2020. Se evaluó en consulta a los dos meses tras el alta con valoración clínica, analítica, serología y radiografía de tórax. Se recogieron los antecedentes, la estancia hospitalaria y la necesidad de UCI. Se definieron síntomas persistentes (SP) como síntomas que aparecieron desde la infección aguda y que se mantenían al seguimiento. Resultados: se revisaron 74 pacientes. La edad media fue 66±13 años, siendo un 51,4% hombres. Seis (8,1%) ingresaron en UCI, y la mediana de estancia fue 8 (6-12) días. Cuarenta (54,8%) presentaron SP, siendo los más frecuentes astenia y disnea (20,3% ambos). Un 77% tenía alteraciones analíticas pero solo en 11 (15,1%) fueron relevantes. Diez (13,5%) presentaban alteraciones radiológicas y 71 (95,9%) tenían IgG positiva. No hubo diferencias entre los pacientes con y sin SP en sus antecedentes o evolución hospitalaria. Los pacientes con SP estaban más taquicárdicos [83 (75-93) lpm vs 76 (65-85) lpm; p=0,038], no existiendo diferencias significativas en el resto de variables... (AU)

Evaluación de la persistencia de síntomas luego de un episodio de infección por SARS-CoV-2 / Characterization of persistent symptoms after SARS-CoV-2 infection

Introducción: Es frecuente que, luego de un episodio de COVID-19, los pacientes persistan con síntomas, lo cual impacta negativamente en su calidad de vida. El objetivo primario de este estudio es determinar los síntomas prevalentes y su duración luego de un episodio de COVID-19 y la persistencia de estos al mes y a los tres meses del episodio. Los objetivos secundarios son describir el lapso entre el episodio de COVID-19, la reinserción laboral o académica y la reanudación de actividad física. Material y métodos: Estudio descriptivo, observacional, en adultos con antecedente de infección por SARS-CoV-2, realizado a través de una encuesta en línea. Se relacionaron variables demográficas y comorbilidades con síntomas durante la infección, al mes y al tercer mes del episodio.Resultados: Participaron 308 personas. Los síntomas más comunes en la fase aguda fueron dolor muscular y fiebre. Al mes, el 89% presentaba síntomas persistentes, siendo los más frecuentes: fatiga y mialgias. Luego de tres meses, 34,85% presentaba síntomas, siendo los más frecuentes: fatiga y anosmia. Solo el 45,7% de las personas logró la reinserción laboral/académica y el 17% de los individuos logró reiniciar actividad física al alta epidemiológica.Discusión: El porcentaje de personas con síntomas persistentes después de un episodio de COVID-19 es alto. La persistencia de los síntomas disminuye con el tiempo, lo cual es un dato alentador para todos aquellos pacientes que consultan por continuar sintomáticos.

Background: It is frequent that patients complain of persistent symptoms after an episode of COVID-19 infection, that worsened their quality of lifeAim: the aim of this study is to describe the main symptoms during a COVID-19 infection and persistent symptoms a month and three months after the episode. Our secondary objective is to describe the period between the COVID-19 episode and resuming work/ studies and exercise routine. Methods: this is a descriptive, observational study that included adults who underwent an episode of SARS-CoV-2 infection. Participants responded to an online survey. We include demographic and comorbidity data and symptoms during infection, and one and three months after infection. Results: 308 people responded to the survey, frequent symptoms during the episode included myalgia and fever. A month after the episode, 89% complained of persistent symptoms, most frequently myalgia and fatigue. Three months after the episode 38.85% complained of persistent symptoms , most frequently fatigue and anosmia. Only 45.7% could resume work/ studies 10 days after the diagnosis, and 17% could resume exercise routine 10 days after the diagnosis. Conclusions: there is a high percentage of people who persisted with symptoms after a COVID-19 infection. We noticed symptoms improved over time, this finding could be encouraged for patients who persist symptomatic after the episode.